Determination of Ginseng Saponin Rg_1,Rb_1,Re and Notoginseng Saponin R_1 in Tangzhiqing Capsule by HPLC
- VernacularTitle:HPLC法测定糖脂清胶囊中人参皂苷Rg_1、Rb_1、Re及三七皂苷R_1的含量
- Author:
Mingqing HUANG
;
Xiangli LI
;
Zhuoming LI
;
Youliang XIE
;
Xuejun ZHAO
;
Ziren SU
;
- Publication Type:Journal Article
- Keywords:
Ginseng saponin Rg_1;
Ginseng saponin Rb_1;
Ginseng saponin Re;
Notoginseng saponin R_1;
HPLC
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a method of determining effective components in Tangzhiqing Capsule.Methods Gin- seng saponin Rg_1,Rb_1,Re and notoginseng saponin R_1 in the capsule were separated and purified by D_(101)macroporous absorption resin,and then determined by HPLC.Results The linearity arrange of ginseng saponin Rg_1,Re,Rb_1 and no- toginseng saponin R_1 were 1.88~11.28?g,1.76~10.56?g,0.294~1.764?g,0.752~2.256?g and the recov- eries were 101.51%(RSD=0.75%),100.58%(RSD=0.46%),100.29%(RSD=1.01%),98.64% (RSD = 0.73%)respectively.Conclusion The method is simple,feasible and reproducible,and can be used for the determination of effective components in Tangzhiqing Capsule.