The therapeutic effects of intermittent hypoxia therapy in isolated systolic hypertension patients
- VernacularTitle:间歇性低浓度氧吸入干预对单纯收缩期高血压患者的疗效观察
- Author:
Ling-Guang WU
;
Jiao-Jie LI
;
Guang LI
;
Meng HU
;
- Publication Type:Journal Article
- Keywords:
Intermittent hypoxia;
Isolated systolic hypertension;
Transcranial doppler ultrasound;
Peak velocity;
Pulsatility index
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the therapeutic effects of intermittent hypoxia therapy(IHT)in isolated systolic hypertension(ISH)patients with elevated cerebral blood flow velocity(Vp),and to explore the mechanisms involved.Methods Seventy-six ISH patients with increasing Vp and normal pulsatility index(PI)of the middle ce- rebral artery(MCA)were randomly divided into a therapy group and a control group.IHT was administrated in the therapy group,and air in the control group.The Vp and PI of the MCA and blood pressure(BP)were observed be- fore and after treatment.Results Vp and systolic blood pressure(SBP)were significantly reduced after IHT(P＜0.01)compared with the therapy group's scores betore treatment,but PI and diastolic blood pressure showed no sig- nificant difference.There was no significant change in BP,Vp or PI in the control group before or after treatment. Conclusion IHT has therapeutic effects on ISH by reducing Vp and moderating SBP.
