Effect of electroacupuncture on bFGF、Ang-2 and Tie-2 expression in rats with cerebral ischemia
- VernacularTitle:电针对脑缺血大鼠碱性成纤维细胞生长因子和血管生成素及其受体表达的影响
- Author:
Xiao-Hua HAN
;
Xiao-Lin HUANG
;
Tie-Cheng GUO
;
Lan YU
;
- Publication Type:Journal Article
- Keywords:
Eleetroacupuneture;
Cerebral ischemia;
Angiogenesis
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of electroacupuncture(EA) on the angiogenesis in rats with cerebral ischemia.Methods 30 male Wistar rats were randomly divided into 3 groups:normal group,model group and EA group.After the establishment of acute middle cerebral artery occlusion(MCAO),the rats were treated with EA on DU20 and DU26.Then the expression of bFGF,Ang-2 and Tie-2 by immunohistochemical staining was ob- served.Results The expression of bFGF and Ang-2 around the infarction locus of EA group increased remarkably compared with normal group and model group and the increase of Tie-2 was not significant.Conclusion EA can increase the expression of bFGF and Ang-2 around the infarction locus and promote the angiogenesis in rats with cere- bral ischemia.
