Preparation of ?-cyclodextrin Inclusion Compound of Volatile Oil from Danfu Tongmai Granules
- VernacularTitle:丹附通脉颗粒中挥发油的?-CD包合工艺研究
- Author:
Qiao'E XIE
;
Shang LI
;
Caihong XIAO
;
- Publication Type:Journal Article
- Keywords:
Orthogonal design;
Danfu Tongmai Granule;
Volatile oil;
?-cyclodextrin
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the inclusion conditions for volatile oil from Danfu Tongmai Granules.Methods With the utilization rate of volatile oil and yield rate of inclusion as indexes,the optimum inclusion conditions were selected by orthogonal design,and the inclusion compound was identified by TLC.Results The optimal inclusion conditions for volatile oil were as follows:a proportion of 1 ∶7(mL ∶g) for oil to ?-cyclodextrin,stirring for 4 hours at 40 ℃.TLC results showed that inclusion process was successful and the main components of volatile oil were similar before and after inclusion.Conclusion This methods can be used for producing ?-cyclodextrin inclusion compound on a large scale.
