Influential factors of systemic lupus erythematosus activity during pregnancy and its relationship with pregnancy outcome
- VernacularTitle:妊娠合并系统性红斑狼疮患者孕期病情活动的影响因素及其与妊娠结局的关系
- Author:
Yun-Hui WANG
;
Xiao-Xia WU
;
Jian-Ping TAN
;
Jian-Ping ZHANG
;
- Publication Type:Journal Article
- Keywords:
Pregnancy complications;
Lupus erythematosus,systemic;
Pregnancy outcome;
Prednisone
- From:
Chinese Journal of Obstetrics and Gynecology
2000;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influential factors of systemic lupus erythematosus(SLE) activity during pregnancy and their relationship with pregnancy outcome.Methods A retrospective analysis of the clinical history of 66 pregnant women with SLE from 1991 to 2005 was carried out.Results(1) Those patients with unstable status progestation,patients being newly diagnosed with SLE during pregnancy or patients irregularly using prednisone became active during pregnancy.The disease was active in 32 cases(the active group)and inactive in 34 cases(the inactive group).(2)Obstetric complications in the active group included:9 cases of preeclampsia,13 cases of fetal growth restriction(FGR),7 cases of therapeutic abortion and 15 cases of premature labor;and the corresponding numbers in the inactive group were 1,5,1 and 4, respectively.All the numbers were significantly different between the two groups(P
