Effects of minimal-invasive installed tube aspiration treatment of hypertensive intracerebral hematoma by rt-PA
- VernacularTitle:rt-PA在高血压脑出血微创置管溶栓引流治疗中的作用
- Author:
Chuanyun QIAN
;
Wei ZHANG
;
Yunhui WANG
;
Wangbin XU
;
Haiying WU
;
- Publication Type:Journal Article
- Keywords:
Hypertensive intracerebral hematoma;
Acute stage;
Thrombolytic therapy;
Urokinase;
rt-PA
- From:
Chinese Journal of Emergency Medicine
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of minimal-invasive installed tube aspiration treatment of hypertensive intracerebral hematoma by rt-PA.Methods Total 71 patients of hypertensive intracerebral hematoma were divided randomly into 3 groups.Group A with 23 patients,which were performed stereotactically placed catheter into the hematoma,and drained consistently;Group B with 24 patients,which were instilled urokinase to liquefy after stereotactically placed catheter and drained the hematoma in 8-hour intervals repeating 3 times over 6 hours;Group C with 24 patients,which were instilled rt-PA to liquefy after stereotactically placed catheter and drained the hematoma in 8-hour intervals repeating 3 times over 6 hours.One week later,the result of head CT scan were compared.Results The volume of hamatoma in CT scan decreased in three groups after therapy.Compared between pre-therapy and post-treatment, difference was significant (P＜0.05),but Group C was the effectivest.Conclusion It was effective and safe that using minimal-invasive installed tube aspiration treatment of hypertensive intracerebral hematoma by rt-PA.
