Immunoregulatory Effects of Polysaccharide of Mudan Cortex on Immunosupressive Mice
- VernacularTitle:牡丹皮多糖对免疫抑制小鼠的免疫调节作用
- Author:
Jinhua WAN
;
Kun-Zhen LI
;
Peng-Ying CHEN
;
- Publication Type:Journal Article
- Keywords:
polysaccharide of Mudan cortex;
Cy;
tumor-bearing;
immunoregulatory activity
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study immunoregulatory activity of polysaccharide of mudan cortex (PSM) on immunodepressive mice. Method The immunodepressive mice model was established with cyclophosphamide treated and tumor-bearing. PSM was orally administered to mice for 10 d. MTT method was used to observe the prolifernation of lymphocytes. The function of macrophage in abdominal activity was measured. Sectrophotometric determination was adopted to evaluate the ability of plaque forming cell. Result PSM could enhance the function of macrophage, increase the content of plaque forming cell, and promote the prelifernation of lymphocytes. Conclusion PSM could enhance immunofunction of immunodepressive mice.
