The research of quantitative salivary gland scintigraphy in the diagnosis of Sjgren's syndrome
- VernacularTitle:~(99m)Tc腮腺动态显像对干燥综合征诊断价值的研究
- Author:
Yi-Li GU
;
Hai-Bo TAN
;
He-Jian ZOU
;
Xing-Dang LIU
;
- Publication Type:Journal Article
- Keywords:
Sjgren's syndrome;
Parotid gland;
Radionuclide imaging
- From:
Chinese Journal of Rheumatology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective The purpose of this study is to determine whether the quantitative parameters of salivary gland scintigraphy are useful in the diagnosis of Sjgren's syndrome(SS).Method Forty patients with SS and 29 control subjects underwent salivary gland scintigraphy.Two indices,uptake ratio and maximum se- cretion were mearsured.The optimal cut-points of both indices were derived from receiver operative character- istic curve(ROC).The diagnostic value of the indices was assessed by the area under ROC curve(AUC~(ROC)). Results The optimal cut-point of uptake ratio was 5.5~5.7.The optimal cut-point of maximum secretion was 0.20.The sensitivities of both indices were 86.2%~89.7%.The specificity of uptake ratio was 63.4%~65.9%. The specificity of maximum secretion was 82.9%~85.4%.The AUC\+\{RoC\} of uptake ratio was 0.780/0,776.The AUC\+\{ROC\} of maximum secretion was 0.905/0,899.Conclusion The quantitative parameters of salivary gland scintigraphy may be useful in the diagnosis of Sj(?)gren syndrome.