Preparation of strychnine solid liposome by sorbitol carrier aggradation and freeze-drying method
- VernacularTitle:山梨醇载体沉积法和冷冻干燥法制备番木鳖碱固体脂质体的研究
- Author:
Taoshi LIU
;
Baochang CAI
;
Xukun DENG
;
Weidong LI
;
Xinhui ZHAO
;
Yaozhou HUANG
;
- Publication Type:Journal Article
- Keywords:
liposome;
strychnine;
freeze-drying method
- From:
Chinese Traditional Patent Medicine
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study preparation of strychnine solid liposome. METHODS: Sorbitol carrier aggradation method and freeze drying method were used to prepare strychnine solid liposomes. They were evaluated by particle morphology, the size range, resolvable peculiarity in the water, encapsulation efficiency. RESULTS: The particles of liposome by sorbitol carrier aggradation method were less than that by freeze drying method, and its encapsulation efficiency was higher than that by freeze drying method. CONCLUSION: Sorbitol carrier aggradation method is better than freeze drying method.
