Analysis of prognostic factors in patients with cervical squamous cell carcinoma of stage Ⅰb and Ⅱa

VernacularTitle:子宫颈鳞癌Ⅰb～Ⅱa期患者预后预测系统的建立及其临床意义
Author: Lu CHEN ; Wei-Guo LV ; Xing XIE ; Huai-Zeng CHEN ; Hua YU ; Xing-Hao NI ;
Publication Type:Journal Article
Keywords: Cervix neoplasms; Carcinoma, squamous cell; Prognosis
From: Chinese Journal of Obstetrics and Gynecology 2001;0(04):-
CountryChina
Language:Chinese
Abstract: Objective To analyze the prognostic factors in patients with cervical squamous cell carcinoma of stage Ⅰb and Ⅱa treated by surgery,and to investigate their guid roles in available post-operation adjuvant therapy. Methods The clinicopathologic records of 306 patients with cervical squamous cell carcinoma of stage Ⅰb and Ⅱa who underwent radical hysterectomy and pelvic lymphadenectomy were retrospectively analyzed, and the prognostic factors were explored by univariate and multivariate methods. Independent prognostic factors were identified by COX proportional hazards regression model. Results The overall 5-year survival rate of these 306 patients was 78.1%. In univariate survival analysis, the poor prognostic factors included poor differentiation, positive pelvic lymph nodes, deep stromal invasion, parametrial extension, tumor size≥4 cm, and lymph vascular space involvement (P