Study on the relationship between regulatory T cells and unexplained recurrent spontaneous abortion
- VernacularTitle:调节性T淋巴细胞与原因不明复发性流产的相关性研究
- Author:
Lihua QIU
;
Qide LIN
;
- Publication Type:Journal Article
- Keywords:
Abortion, spontaneous;
CD 4 positive T lymphocytes;
Receptors, interleukin ?
- From:
Chinese Journal of Obstetrics and Gynecology
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between CD + 4CD + 25 regulatory T cells (CD + 4 CD + 25 Tr)and unexplained recurrent spontaneous abortion (URSA) Methods The expression rate of CD + 4CD + 25 Tr in peripheral blood was determined by double label flow cytometric analysis The samples were taken from 20 normal non pregnancy women, 17 URSA women and 20 normal pregnancy women Results The expression frequency of CD + 4CD + 25 Tr cells was decreased significantly( P 0 05) Conclusion The results suggest that downregulation of CD + 4CD + 25 Tr may be associated with URSA
