Study of esomeprazole and rabeprazole on 24-hour intragastric acid control in healthy volunteers
- VernacularTitle:埃索美拉唑对健康志愿者抑制胃泌酸的药效学研究
- Author:
Xianbao ZHAN
;
Zhaoshen LI
;
Nengneng CHENG
;
Al ET
;
- Publication Type:Journal Article
- Keywords:
Esomeprazole;
Rabeprazole;
Intragastric pH;
CYP 2C19
- From:
Chinese Journal of Digestion
2001;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
4 was found significantly higher in esomeprazole group than in rabeprazole group during first 4 hours (58.9% vs 32.1%), 24 hours on day 1 (73.7% vs 54.8%) and 24 hours on day 5 (84.2% vs 76.2%) (P 4 for at least 16 hours on day 1 and day 5 was higher in esomeprazole group than in rabeprazole group (day 1 63.9% vs 33.3%, day 5 88.9% vs 61.1%, P