Quality standard for Qingreling Granules
- VernacularTitle:清热灵颗粒质量标准研究
- Author:
Benliang LIU
;
Lei ZHAO
;
Fuxiang WU
;
Jian LIU
;
- Publication Type:Journal Article
- Keywords:
Qingreling Granules;
baicalin;
TLC;
RP HPLC
- From:
Chinese Traditional Patent Medicine
1992;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To establish the quality control standard of Qingreling Granules (Radix Scutellariae, Fructus Forsythiae, Folium Isatidis, Radix Glycyrrhizae). METHODS: Fructus Forsythiae, Folium Isatidis, Radix Glycyrrhizae in Qingreling Granules were identified by TLC. The baicalin content in Qingreling Granules were detemined by RP HPLC with C 18 reversed phase column, methanol water phosphoric acid (65∶31∶4) as a molile phase, the detection wavelength at 280nm and flow rate at 1.0mL?min -1 . RESULTS: Baicalin showed a good relationship at a range of 0.0464～0.464?g( r =0.9996). The average recovery of baicalin in Qingreling Granules was 97.2% and RSD was 1.25% ( n =5). CONCLUSION: The method is simple, specific and accurate. This study provide a method for the quality control of Qingreling Granules.
