The experimental study on the healing quality of the stoma in esophagogastrostomy by layering anastomosis
- VernacularTitle:食管胃分层吻合法吻合口愈合质量的实验研究
- Author:
Chenhao XIE
;
Yongfan ZHAO
;
Yingling KOU
;
Al ET
;
- Publication Type:Journal Article
- Keywords:
Esophagus Anastomoses,surgical Epidermal growth factor Transforming growth factor beta
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
1995;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe prespectively the healing quality in esophagogastrostomy anastomosis by layers. Methods The 12 dogs (adult male healthy hybrid dogs, group A) underwent esophagectomy with anastomosly layer. The anastomosis were observed grossly and histologic study was made on 5th, 8th, 14th, and 42th postoperative day (POD). The expression of the cytokines relating to wound healing such as epidermal growth factor(EGF), transforming growth factor ? 1(TGF ? 1) were detected (Immunohistochemistry, LsAB technique). Another 12 dogs underwent the intermittent whole layer with silk (group B). Results In group A, the stoma mucosa were in a better cooperation, soft, and had a thin scar. The count of the inflammation cells and fibroblast increased at the early period of postoperation (P
