Effects of Guizhi Fuling Capsule on prostatic hyperplasia in experimental rats
- VernacularTitle:桂枝茯苓胶囊对实验性大鼠前列腺增生的影响
- Author:
Chunyu LIU
;
Jianxin PAN
;
Keping ZHANG
;
Feng HAN
;
Zhenlun GU
;
- Publication Type:Journal Article
- Keywords:
Guizhi Fuling Capsule (GFC);
testesterone propionate;
prostatic hyperplasia
- From:
Chinese Traditional and Herbal Drugs
1994;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Object To observe the effect of Guizhi Fuling Capsule (GFC) on prostatic hyperplasia in rats induced by testosterone propionate. Methods Seven days after the male rats were castrated, testosterone propionate (3 mg/kg) was sc injected in rats. Meanwhile, the rats were administered GFC (2.16, 1.08, 0.54 g/kg) once a day, and the treatment continued for 30 d. An hour after the final administration, the rats were put to death, and the weight and volume of prostates were measured. The construction of prostate cells was also observed under light microscope. Results In the GFC group, the weight and volume of prostate was significantly decreased compared with that in the model group (P