Clinical study of percutaneous transhepatic bile duct biopsy in obstructive jaundice
- VernacularTitle:对阻塞性黄疸行胆道活检的临床研究
- Author:
Xinwei HAN
;
Yongdong LI
;
Bo MA
;
Al ET
;
- Publication Type:Journal Article
- Keywords:
Percutaneous transhepatic cholangiography;
Obstructive jaundice;
Neoplasm;
Bile duct biopsy;
Pathology
- From:
Chinese Journal of Digestion
1998;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the technical feasibility and sensitivity of percutaneous bile duct biopsy in obstructive jaundice. Methods Eighty two consecutive patients with obstructive jaundice underwent transluminal bile duct biopsy and brushing since April 2001. The technique was performed through an existing percutaneous transhepatic tract. Multiple specimens were obtained after passing the forceps biopsy or brush into a long 8 French sheath and the specimens were fixed with formalin for pathologic or cytologic diagnosis. Results The successful rate of obtaining specimen with biopsy was 97.6%. There was no major complications occurred. The histopathologic diagnosis was established acquired in 72 of 82 patients with forceps biopsy(sensitivity 87.8%). Sensitivity of biopsy in the 56 patients with cholangiocarcinoma was higher than that in the 22 patients with malignant tumors other than cholangiocarcinoma (92.9% vs. 72.7% P =0.044). The cytologic diagnosis was established in 56 of 74 patients with brush cytology(sensitivity 75.7%). The sensitivity of biopsy in the 82 patients was higher than that of brushing in the 74 patients (87.8% vs. 75.7%, P = 0.049 ). Conclusion Percutaneous transhepatic bile duct biopsy is a simple, minimal invasion, high sensitivity and low complication procedure with high technical successive rate. It is a new approach to establish pathologic diagnosis
