Evaluating the efficacy of transcatheter arterial chemoembolization combined with hypofractionated 3- dimensional conformal radiotherapy for hepatocellular carcinoma
- VernacularTitle:介入治疗结合大分割三维适形放射治疗原发性肝癌的疗效评价
- Author:
Dehua WU
;
Fachao ZHI
;
Longhua CHEN
;
- Publication Type:Journal Article
- Keywords:
Liver neoplasm;
Radiotherapy;
Embolization;
3-dimensional conformal radiation
- From:
Chinese Journal of Digestion
1998;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of transcatheter arterial chemoembolization (TACE) combined with hypofractionated 3 dimensional conformal radiotherapy for hepatocellular carcinoma (HCC). Methods During May 1998 and Dec. 1999, 81 unresectable HCC patients were divided into two groups. Forty one patients in group A were treated with TACE and hypofractionated 3 dimensional conformal radiotherapy and 40 patients in group B were treated with TACE alone. Acute effects were analyzed and survival rates were assessed from the date of the beginning of treatment using the Kaplan Meier method. The survival rates of two groups were compared using Log rank. The Cox proportional hazards model was used to analyze the prognostic factors in group A. Results The objective response rate in group A was higher than that in group B (85.4% vs. 65.0% , P