Intra-artery thrombolytic therapy for acute ischemic cerebral infarction
- VernacularTitle:动脉内溶栓治疗急性缺血性脑梗死
- Author:
Wei DU
;
Chengmin SHAO
;
Jianlin WANG
;
Al ET
;
- Publication Type:Journal Article
- Keywords:
Cerebral infarction;
Thrombolysis;
Interventional treatment
- From:
Journal of Interventional Radiology
1994;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical effects of intra arterial thrombolytic therapy for acute ischemic cerebral infarction and analize the factors influencing the clinical prognosis. Methods 32 patients were treated with intra arterial thrombolysis using urokinase(median dose, 65?10 4 U) within 2～20 hours, after the onset. The patient's condition was assessed by neurologists using National Institutes of Health Stroke Scale(NIHSS) score right at the admission. Clinical outcome was assessed after 3 months and graded as good for Modified Rankin Scale(MRS) scores of 0 to 3 and poor for MRS scores of 4 or 5 and death. Results Follow up cerebral angiography of 14 cases treated within 6 hours after onset showed complete/partial recanalization in 13 cases. Other 18 patients whose treatment started beyond 6 hours after onset outcame with complete/partial in 7. 20(62.5%) of the 32 patients had good outcome, 12(37.5%) had poor outcome and two patients(9.4%) died. Cerebral hemorrhage occurred in 2 of the 32 patients. Good outcome was associated with an initial NIHSS score of
