Transarterial lidocaine-lipiodol emulsion administration for relief of pain during transarterial chemoembolization of malignant tumor
- VernacularTitle:经动脉内灌注利多卡因-碘油乳剂在恶性肿瘤栓塞化疗术中止痛疗效的评价
- Author:
Anle WU
;
Zhiping YAN
;
Kangrong ZHOU
;
Al ET
;
- Publication Type:Journal Article
- Keywords:
Pain;
Malignant tumor;
Lidocaine
- From:
Journal of Interventional Radiology
1994;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the feasibility and efficacy of transarterial lidocaine lipiodol emulsion administration for controlling abdominal pain and preventing the arterial spasm resulting from TACE, and to evaluate the optimal amount of lidocaine administration. Methods In a prospective trial of 120 consecutive patients with malignant tumor who underwent TACE were divided into three groups, those who received lidocaine lipiodol emulsion administration (group A, n =40), those who received lidocaine bolus intraarterial infusion immediately before TACE (group B, n =40) and those who received no lidocaine injection before TACE, (group C, n =40). The degree of post procedure pain was evaluated by a subjective method (using visual analogue scales from 0 to 10), and an objective method (amount of post procedure analgesics). Incidence and degree of arterial spasm were assessed by DSA. Results The correlative pain incidences between the three groups showed significant difference ( P 0.05). Mean dose of intramuscular analgesics for controlling intolerable pain in group A and B was significantly lower than that of group C ( P
