Effect of abirritation,anti-inflammation and gastrointestinal peristalsis inhibition of Zhongjingweiling Capsules
- VernacularTitle:仲景胃灵胶囊镇痛抗炎抑制胃肠蠕动作用研究
- Author:
Murong YE
;
Yongheng TAN
;
Xuezhen LIAO
;
Huifang LIAO
;
Jiuyao ZHOU
;
- Publication Type:Journal Article
- Keywords:
Zhongjingweiling Capsule;
analgesia;
anti inflammation;
gastrointestinal peristalsis inhibition;
mouse;
rat
- From:
Chinese Traditional Patent Medicine
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the effects of Zhongjingweiling Capsule (Fructus Amomi, Cortex Cinnamemi, Rhizoma Alpiniae Galangae, Fructus Foeniculi, Radix Glycyrrhizae, etc.) on analgesia, anti inflammation and gastrointestinal peristalsis inhibition. METHODS: The effect of analgesia was tested by the method of writhes and hot plate on mice. The effect of anti inflammation was tested by injecting acetic acid and implanting cotton pellet and xylene into mice. RESULT: Zhongjingweiling Capsule effectively inhibited the swelling of mouse pinna induced by xylene and the increase of peritoneal capillary permeability caused by the acetic acid injected into mice. The capsule also decreased the proliferation of granuloma caused by implantation cotton pellet significantly and had an abirritant effect on the algesia induced by acetic acid and hot plate. Besides, it effectively inhibited the gastrointestinal peristalsis. CONCLUSION: Zhongjingweiling Capsule is an effective medicine in anti inflammation, analgesia, and gastrointestinal peristalsis inhibition.
