Experimental study of Dachuanxiong Decoction on injury induced by ischemia in nerve cells
- VernacularTitle:大川芎方对神经细胞缺血性损伤的保护作用
- Author:
Gan YAO
;
Cheng PENG
;
Dong ZHOU
;
Yitao WANG
;
- Publication Type:Journal Article
- Keywords:
Dachuanxiong Decoction, cell cultivation;
injury induced by ischemia
- From:
Chinese Traditional Patent Medicine
1992;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the protective effects of Dachuanxiong Decoction (Rhizoma Chuan Xiong, Rhizoma Gastrodiae, etc) on injury induced by ischemia in nerve cells. METHODS:The level variation of activity and calcium ions of nerve cell were observed, choosing nerve cell ischemia model with hypoxia device and adapting confocal laser scanning microscopy and MTT method.. RESULTS:Dachuanxiong Decoction adjusted the abnormal structure of ischemia nerve cell, inhanced the survival rate and nerve call's, activity and decreased the concentration of calcium ions of nerve cell. CONCLUSION: Dachuanxiong Decoction blocked the calcium ion channels, nourished and protected nerve cells from ischemic injury.
