Study on fingerprint for the quality control of Banlangen Granule
- VernacularTitle:板蓝根颗粒的指纹图谱质量控制研究
- Author:
Lingjie ZENG
;
Dongsheng YANG
;
Songguang CHEN
;
Mao CHEN
;
- Publication Type:Journal Article
- Keywords:
Isatis indigotical Fort;
fingerprint;
amino acids;
HPLC
- From:
Chinese Traditional Patent Medicine
1992;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To establish a fingerprint analytical method for ensuring the quality of Banlangen Granule (Isatis indigotica Fort). METHODS: According to pre column derivatization HPLC method, gradient elution with sodium acetate buffer (pH6.4) acetonitrile (95∶5) in a BDS C 18 column, was applied to detect amino acid at UV 360nm; and the coefficients of cosine of include angle and distance were employed to judge the quality similarity of the samples. RESULTS: The HPLC method is accurate and reproducible and makes almost all the peaks separated; and the two coefficients can show the similarity of each sample. CONCLUSION: The developed method is simple, accurate and operable and can efficiently control the quality of Banlangen Granule.
