Circulating endothelial cells and hepatocyte growth factor in patients with pregnancy induced hypertension
- VernacularTitle:妊娠高血压综合征患者血中循环内皮细胞及肝细胞生长因子的变化及意义
- Author:
Yan WANG
;
Tao SHANG
;
Weiwei TANG
;
- Publication Type:Journal Article
- Keywords:
Endothelium, vascular;
Hepatocyte growth factor;
Pregnancy complications, cardiovascular;
Hypertension
- From:
Chinese Journal of Obstetrics and Gynecology
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between hepatocyte growth factor (HGF) and vascular endothelial cells (VEC) in pregnancy induced hypertension (PIH) Methods Twenty women with PIH (6 mild, and 14 moderate or severe PIH ) and 20 women with normal pregnancy were recruited as study group and control group, respectively The two groups were matched in maternal age, parity and gestational age Flow cytometer was used for counting the number of peripheral blood circulating endothelial cells (CEC), while enzyme linked immunoadsordent assay (ELISA) was used to measure the concentration of serum HGF Results In the study group, the concentration of HGF was (1395?512) ng/L, and the number of CEC was (109 360?24 070) /L In the control group, the concentration of HGF was (1565 ?399) ng/L, and the number of CEC was (21 800?4420)/L The differences both in the concentration of HGF and the number of CEC between the two groups were statistically significant ( P
