EXPRESSION OF EGF AND PCNA DURING THE DEVELOPMENT OF HUMAN FETAL TESTIS
- VernacularTitle:人胎儿睾丸发生过程中表皮生长因子与细胞增殖核抗原的表达
- Author:
Siyun NIU
;
Fulu GAO
;
Xiaojing PANG
;
Xiuhua LI
;
- Publication Type:Journal Article
- Keywords:
Testis;
EGF;
PCNA;
Immunocytochemistry;
Fetus
- From:
Acta Anatomica Sinica
2002;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the expressing features of EGF and PCNA and study their roles during the development of human fetal testis. Methods The positive rates of EGF and PCNA in Leydig cells,Sertoli cells and germ cells of human fetal testis from 12th to 32th week were examined by SP immunocytochemical technique. Results The positive cells of EGF were not found in 12th week,and were found in Leydig cells from 16th to 32th week,the peak of expression was observed in 16th week.The positive staining was orange or brown and were scattered within the cytoplasm,the number of positive cells decreased gradually with the increasing of the fetal ages (P
