Extract from cultured cells of Taxus chinensis on proliferation inhibition and apoptosis induction of tumor cells
- VernacularTitle:红豆杉细胞提取物抑制肿瘤细胞增殖及诱导凋亡的实验研究
- Author:
Cuitao LU
;
Yingzheng ZHAO
;
Xingguo MEI
;
- Publication Type:Journal Article
- Keywords:
cell of Taxus chinensis (Pilg.) Rehd.;
SMMC 7721;
cell proliferation;
cell apoptosis
- From:
Chinese Traditional and Herbal Drugs
1994;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Object To study the inhibitory effect and mechanism of extract from cultured cell of Taxus chinensis (Pilg.) Rehd. on hepatocarcinoma cell line SMMC 7721. Methods Trypan blue stain assay was used to determine tumor cell growth curve, flow cytometry and Giemsa staining were used to analyze cell cycle and cell apoptosis. Results Inhibitory effect happened on tumor cell line SMMC 7721, G 2/M stage of tumor cells increased with the addition of T. chinensis cell extract by carrene and apoptosis happened. Conclusion The extracts from cultured cell of T. chinensis have inhibitory effect on SMMC 7721 cells and can further induce cell apoptosis.
