Expression of NF-?B in the lungs of adjuvant arthritis rats
- VernacularTitle:核因子?B在佐剂性关节炎大鼠肺组织中的表达
- Author:
Hui SHEN
;
Xiubin FANG
;
- Publication Type:Journal Article
- Keywords:
Arthritis,experimentel;
Arthritis,rheumatoid;
NF kappa B
- From:
Chinese Journal of Rheumatology
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of NF ?B in the lungs of adjuvant arthritis (AA) rats and to explore its possible role in the pathogenesis of rheumatoid arthritis (RA) pulmonary involvement.Methods The level of active NF ?B protein was detected by Western blot and the level of NF ?BmRNA by in situ hybridization histochemistry The intensity of expression was analyzed by micro image analysis system.Results The levels of active NF ?B protein and NF ?B mRNA in the lungs of AA rats were much higher than those of the controls ( P
