A Study on Quality Standard of Compound Huangqin Tablets
- VernacularTitle:复方黄芩片质量标准的研究
- Author:
Yuan'Er ZENG
;
Wenbiao LU
;
Jingjin ZHONG
;
- Publication Type:Journal Article
- Keywords:
Compound Huangqin Tablets/chemistry;
Radix Scutellariae /chemistry;
Rhizoma Polygonim Cuspidati/chemistry;
Caulis mahoniae /chemistry;
Baicalin/analysis;
Chromatography,thin layer
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish the standard for the quality control of Compound Huangqin Tablets. Methods The identification of Radix Scutellariae,Rhizoma Polygoni Cuspidati and Caulis Mahoniae in compound Huangqin tablets were carried out by TLC.The content of baicalin in the preparation was determined by HPLC.Chromatocolumn was adopted,methanol-0.4 %H3PO4(50 ∶50) used as the mobile phase,flowrate 1.4mL/min,column temperature at 40 ℃and detection wavelength 278 nm . Results The TLC spots were highly clear without the interference of negative control and were reproductive. The calibration curve for baicalin was linear (r=0.9996) in the range of 0.12～0.72 ?g and the mean recovery was 97.17 %and RSD=1.78 %(n=5). Conclusion This method can be used for the quality control of Compound Huangqin Tablets.
