In vitro hemodynamic evaluation of the cryopreserved stented homograft bioprosthetic heart valve
- VernacularTitle:液氮保存同种带支架人工瓣膜流体力学测试
- Author:
Zhiqiang LI
;
Yinglong LIU
;
Xiaodong ZHU
;
- Publication Type:Journal Article
- Keywords:
Heart valve prosthesis Cryopreservation Hemodynamic
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2003;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate hemodynamic function of the cryopreserved stented homograft bioprosthetic valve , compared to Perfect bovine pericardial bioprosthetic heart valve. Methods: Three sorts of stented homograft aortic and pulmonary valve (21 #, 23 #, 25 #) preserved by liquid nitrogen were prepared. In vitro pulsatile flow tests were performed on the valve in accordance with ISO/FDA guideline. Effective orifice area (EOA), transvalve pressure gradient and regurgitation ratio were recorded at various flow volume, compared with Perfect bioprosthetic valve. Results: There was no difference between the transvalve pressure gradient of the stented homograft aortic and pulmonary valve, but they were higher than Perfect bioprosthetic valve. The stented homograft aortic and pulmonary valve showed the larger regurgitation ratio than perfect valve, but there was no difference between two types of valve. EOA of the stented homograft aortic and pulmonary valve were smaller than Perfect valve's, there was no discrepancy between them. Though actual orifice area (AOA) of the stented homograft valve was smaller than Perfect's, but EOA/AOA ratio was no difference between two types of valve.Conclusion: The stented homograft valve has satisfactory hemodynamic performance. There is no significant discrepancy between homograft aortic and pulmonary valve's hemodynamic function.