Effect of triptolide on the expression of CD86 on systemic lupus erythematosus B cells
- VernacularTitle:雷公藤内酯醇对系统性红斑狼疮病人B细胞表达CD86分子的影响
- Author:
Ruihong XU
;
Tangde ZHANG
;
Qingsong ZHAN
;
Yi TAO
;
- Publication Type:Journal Article
- Keywords:
Lupus erythematosus,systemic;
B Lymphocytes;
Tripterygium
- From:
Chinese Journal of Rheumatology
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of CD86 on systemic lupus erythematosus (SLE) peripheral B cells and the effect of triptolide (TL) on it.Methods The percentage of CD86 + B cells was detected by flow cytometer when the peripheral blood mononuclear cells (PBMC) was freshly seperated or after cultured with TL in different concentration for 48 hours.Results The percentage of CD86 + B cells of SLE patients was higher than that of normal controls either when the PBMC was freshly separated ( P
