Investigate the dynamic change of tetramethylpyrazine in processing of Chuangxiongchatiao Granules
- VernacularTitle:HPLC考察川芎茶调颗粒制备中川芎嗪的动态变化
- Author:
Hui GUI
;
Jingren XIAO
;
Long ZOU
;
- Publication Type:Journal Article
- Keywords:
Chuangxiongchatiao Granules;
tetramethylpyrazine;
dynamic change;
HPLC
- From:
Chinese Traditional Patent Medicine
1992;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the dynamic change of tetramethylpyrazine (TMP) in processing of Chuangxiongchatiao Granules. Methods: To explore the influences of the different extraction, concentration and drying method on the transferring rate of TMP by HPLC. Results: Transferring rate of TMP is higher by alcohol than by water. The loss of TMP in concentrating process is lower by rotating distillation than by direct heating concentration and by reduced pressure concentration. The transferring rate of TMP is higher by reduced pressure desiccation than by ordinary pressure. Conclusion: The better extrating way of Chuangxiong is by alcohol in the processing of Chuangxiongchatiao Granules; the concentrating and drying process should be done at the low temperature and by rapid dry process.
