Study on quality standard for Jinzhitai Capsule
- VernacularTitle:金脂泰胶囊质量标准研究
- Author:
Xiaoqiang YE
;
- Publication Type:Journal Article
- Keywords:
Jinzhitai Capsule;
TLC;
emodin;
chrysophanol;
physcion;
HPLC
- From:
Chinese Traditional Patent Medicine
1992;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To establish a quality standard for Jinzhitai Capsule(Rhizoma Polygonati, Radix Polygoni Multiflori Preparata, Rhizoma Alismatis, alcohol extract of Gynostemma Pentaphyllun, Fructus Crataegi, Semen Cassiae, etc.). Methods: Radix Polygoni Multiflori Preparata, Rhizoma Alismatis, Semen Cassiae were identified by TLC. The content of emodin and chrysophand and physcion in Jinzhitai Capsule were determined by HPLC, using a Kroma. sil C 18 column, methanol 0.1% phoaphoeic acid(94∶6) as the mobile phase. The detection wavelength was 440nm. Results: The TLC spots developed were quite clear. The linear ranges of emodin and chrysophanol and physcion were 0.039～0.35?g and 0.039～0.35?g and 0.037～0.33?g, respectively. The average recovery of emodin and chrysophanol and physcion was 97.4% and 98.0% and 97.1%, with RSD of 1.70% and 1.56% and 1.83%, respectively. Conclusion: The method can be used to the quality control of Jinzhitai Capsule.
