Determination for 5-HMF in Glucose Injection containing the extract of Radix Salviae Miltiorrhizae
- VernacularTitle:含丹参的葡萄糖注射液中5-羟甲基糠醛的检查方法研究
- Author:
Xiaobin JIA
;
Xiaolei WAN
;
Baochang CAI
;
Yan CHEN
;
- Publication Type:Journal Article
- Keywords:
Hydroxymethyl furfuraldehyde(5 HMF);
Danshen Glucose Injection;
Xiangdan Glucose Injection;
HPLC
- From:
Chinese Traditional Patent Medicine
1992;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To establish the determination for 5 HMF in Glucose Injection containing the extract of Radix Salviae Miltiorrhizae. Methods: Using HPLC with Hypersil ODS [4.6mm(i.d)?250mm] column, methanol 0.5% acetic acid as a mobile phase and detection wavelength at 284nm. Results: The peak of 5 hydroxymethylfurfural was separated from the peak of Danshensu. Conclusion: The method is simple, sensitive and accurate with a good reproducibility and can be used as the quality control for Glucose Injection containing the extract of Radix Salviae Miltiorrhizae.