Study on quality standard for Fufang Jiangya Liniment
- VernacularTitle:复方降压搽剂的质量标准研究
- Author:
Qingfei LIU
;
Liling ZHOU
;
Xin FAN
;
- Publication Type:Journal Article
- Keywords:
Fufang Jiangya Liniment;
quality standard;
TLC;
GC;
RP HPLC
- From:
Chinese Traditional Patent Medicine
1992;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To establsh the quality standard for Fufang Jiangya liniment (Folium Apocyni Veneti, Semen Cassiae, Semen Vaccariae, etc.). Methods: Semen Cassiae, Folium Apocyni Veneti and Semen Vaccariae were identified by TLC. Fructus Coriandri was identified by GC. Chrysophanol and quercetin were determined by RP HPLC. Results: The petroleum ether (boiling range: 30～60?C) n hexane ethyl acetate formic acid (1∶3∶1.5∶0.01) was used as the developer for the identification of Semen Cassiae on silica gel G coating plate. The toluene ethyl acetate formic acid (5∶4∶1) was used as the developer for the identification of Folium Apocyni Veneti and Semen Vaccariae, respectively, also on silica gel G coating plate. By GC, licareol as standard substance, Fructus Voriandri could be identified. By RP HPLC, kromasil C 18 as fixed phase, when methyl alcohol water perchloric acid (80∶20∶0.1) was used as the mobile phase. ( ? =257nm), the average recovery of chrysophanol was 0.0298mg?mL -1 , methyl alcohol 0.5% phosphoric acid solution (1∶1) was used as the mobile phase ( ? =370nm), the average recovery of quercetin was 1.1522mg?mL -1 . Conclusion: The methods established are simple, feasible and reproducible and can be used as the quality standards for Fufang Jingya Liniment.
