Effect of Congsheng Capsule on free radical change after cerebral ischemia-reperfusion in mice
- VernacularTitle:聪圣胶囊对小鼠脑缺血再灌注损伤后自由基变化的影响
- Author:
Ling ZHAO
;
Qiuping XU
;
Lin LI
;
- Publication Type:Journal Article
- Keywords:
Congsheng Capsule;
cerebral ischemia;
free radical;
NO
- From:
Chinese Traditional and Herbal Drugs
1994;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Object To investigate the effects of Congsheng Capsule (CSC) on free radical change after cerebral ischemia reperfusion, and analyze the mechanisms of CSC anti cerebral ischemia action. Methods Bilateral carotid artery occlusion and reperfusion combined with tail bleeding hypotension were employed in this study. Changes in free radicals were observed by means of spectro photometry. Results CSC 1, 3, 9 g/kg could enhance SOD activity, reduce the MDA content, and decrease NOS activity and NO content. Conclusion The protective effects of CSC on cerebral ischemia may be mediated by its anti free radical and NO damage.
