Effects of oxytocin,misoprostol and nimodiping on expression of L-type voltage dependant calcium channel mRNA of the uterine myometrium and left ventricular myocardial cells in late pregnant rats
- VernacularTitle:不同药物对晚孕鼠子宫平滑肌及左心室心肌细胞电压依赖性钙通道-L亚型mRNA表达的影响
- Author:
Weishe ZHANG
;
Liangxiang CHEN
;
Zhaodi WU
;
Jiangxian LIU
;
- Publication Type:Journal Article
- Keywords:
Uterus;
Muscle,smooth;
Myocardium;
Calcium channels,L type;
Pharmaceutical prepartions;
Labor;
Pregnancy,animal
- From:
Chinese Journal of Obstetrics and Gynecology
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). Conclusions Oxytocin, misoprostol or nimodipine can induce or inhibit labor through regulating expressions of VDCC L ? 1 and VDCC L ? 2 mRNA in the rat uterine myometrium and it may not have an adverse effect on heart function of normal pregnant rats. VDCC L may be the common channel of labor induced by internal or external factors.
