Effect of Tianmashouwu Tablet on migraine
- VernacularTitle:天麻首乌片治疗偏头痛的作用机理的实验研究
- Author:
Zhaohui LIU
;
Changquan ZHOU
;
Baofan YANG
;
Dong HAN
;
Fulong LIAO
;
- Publication Type:Journal Article
- Keywords:
Tianmashouwu Tablet;
ET;
NO;
migraine
- From:
Chinese Traditional Patent Medicine
1992;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To discover the connection between migraine and Tianmashouwu Tablet (TMT) in endothelial cell perspective. Methods: Serum containing TMT was added to rat's cerebral capilary endothelial cell's culture to observe the changes of NO and ET, and effect on express of ETmRNA and iNOSmRNA. Results: Levels of iNOSmRNA, rCMECs and ETmRNA were all downregulated, and contents of both NO and ET were decreased. Conclusions: TMT is effective in protection against rCMECs induced apoptosis, and has a therapeutic effect on migraine.
