Study on release of slow-released tablets of puerarin
- VernacularTitle:葛根素缓释片释放度的研究
- Author:
Qiufang JING
;
Fuzheng REN
;
Yongjia SHEN
;
- Publication Type:Journal Article
- Keywords:
puerarin;
slow released tablet;
release rate
- From:
Chinese Traditional and Herbal Drugs
1994;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Object To study the release mechanism of slow released tablet of puerarin (PUE) prepared by taking chistosan (CS) and sodium alginate (AL) as primary excipient. Methods The effect of the release in different conditions and the release mechanism was observed. Results No effect was found on release rate by basket and blade paddle methods, but the primary release (1 2 h) in different rotation speed showed the effect on drug release and the release rate was dependent on medium pH value (P