Study on extracting process and formulation of Mashi Granules
- VernacularTitle:麻石颗粒提取工艺及制剂处方组成的研究
- Author:
Jun LI
;
Dianjia SUN
;
Jiaguo LIU
;
Lisha ZHU
;
Liang TENG
;
- Publication Type:Journal Article
- Keywords:
Mashi Granules;
extraction;
area under curve of lowered temperature;
the uniformity design
- From:
Chinese Traditional Patent Medicine
1992;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To ascertain the process condition of extraction Mashi Granules(Herba Ephedrae, Gypsum Fibrosum, Radix Puerariae, Herba Methal, Semen Armeniacae Amerum, etc.) Methods: In combination with area under the curve of hypothermy in rabbits, process water, macerating time and boiling times were used as parameters in uniformidy design. And then appropriate excipients were selected on the basis of hygroscopicity and granulation. Results: 20 times amount of water as much as herbs was added, macerating time reached as far as 40 min, and extracted 3 times, 2h a time. Excipient formula consisted of lactose and mannitol(4∶1, w/w). Conclusion: The experimental results provide the basis for the ascertainment of extracting process and formulation of Mashi Granules.
