Extraction of three kinds of volatile oil and preparation of ?-CYD inclusion compound of Yuxianling Granules
- VernacularTitle:愈痫灵颗粒剂中3种挥发油的提取及?-环糊精包合物的制备研究
- Author:
Qun HE
;
Jingjing WANG
;
Yan ZHONG
;
Xing GU
;
Zhenguang LI
;
Zuzhen DUAN
;
- Publication Type:Journal Article
- Keywords:
Yuxianling Granules;
volatile oil;
extraction;
inclusion
- From:
Chinese Traditional Patent Medicine
1992;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To specify optimize condition of process for mixture extraction of three kinds of volatile oil and preparation of ? CYD inclusion compound of Yuxianling Granules.Methods: Taking weight of volatile oil to evaluate the extraction process and percentage recovery of inclusion compound, transfer rate of oil, inclusion rate of oil to evaluate the inclusion process. Orthogonal design was applied. Results: The optimum extraction condition was to add five times amount of water into the mixture of crude drugs, to soak for 90 min, to heat up to boiling and reflux 4h. The trituration method is suitable for the productive preparation of inclusion compound, the optimum inclusion condition was ? CYD: Volatile oil in proportion as 8∶1 was mixed, adding two times amount of water into the mixture and trituration 30 min.Conclusions: Above condition of process was the most rational in extraction and inclusion of three kinds of volatile oil.
