Technical condition of semi-bionic extraction in optimizing formula of Jiaotai Pill through homogeneous design
- VernacularTitle:均匀设计优选交泰丸方药的半仿生提取工艺条件
- Author:
Xuelan ZHANG
;
Zhaowang ZHANG
;
Chunqiang LIU
;
- Publication Type:Journal Article
- Keywords:
Jiaotai Pill;
semi bionic extraction;
homogeneous design;
extraction condition
- From:
Chinese Traditional Patent Medicine
1992;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To optimize the extraction condtions in the modification of the formula of Jiaotai Pill. Methods: The semi bionic extraction (SBE) conditions were optimized through homogeneous design while berberine, cinnamic acid, total alkaloids, volatile oil and dry extract were adopted as markers. Results: PH in first extraction was adjusted to 2.20 by the use of HCL solution. And then PH in second and third extraction adjusted to 6.50 and 7.80 , duration of run was 170 min, 80 min and 40 min, respectively. Conclusion: Semi bionic extraction in Jiaotai Pill is approximated to theoretical extraction value.