Study on the protection of Yufeng Capsule on activity of ATPase in brain tissue of rat with ischemia-reperfusion
- VernacularTitle:御风胶囊对缺血再灌注大鼠脑组织ATPase活性保护作用的研究
- Author:
Ying ZHAO
;
Zhongren SUN
;
Wei WANG
;
- Publication Type:Journal Article
- Keywords:
Yufeng Capsule;
ischemia reperfusion;
cerebral edema;
ATPase
- From:
Chinese Traditional Patent Medicine
1992;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the effect of Yufeng Capsule (Radix Astragali, Radix Salviae Mitiorrhizae, Rhizoma Gastrodiae, etc) on the moisture content, activity of Na +,K + AT Pase and Ca 2+ ATPase in brain tissue of rat with ischemia reperfusion.Methods:the model with ischemia reperfusion was established by line embolism method, the moisture content and activity of ATPase in brain tissue of model rat were determined respectively at ischemia 2h reperfusion 1h and ischemia 2h reperfusion 24h.Results:Yufeng Capsule could significantly decrease moisture content of rats brain, increase the activity of Na +,K + ATPase and Ca 2+ ATPase.Conclusion:Yufeng Capsule could prevent and treat the cerebral edema caused by ischemia reperfusion, its mechanism may be related to improving cytomembrane ionic transport after ischemia reperfusion.
