Study on pharmacodynamics of Chinese herbal drug Guijiu and its lignan
- VernacularTitle:鬼臼类中药及其木脂素类成分的药效学研究
- Author:
Mingying SHANG
;
Luoshan XU
;
Ping LI
;
Guojun XU
;
Yixian WANG
;
Shaoqing CAI
;
- Publication Type:Journal Article
- Keywords:
Guijiu;
lignan;
antitumor effect
- From:
Chinese Traditional and Herbal Drugs
1994;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Object To study the antitumor effects of extracts from the fruits, roots and rhizomes of Sinopodophyllum emodi (Wall.) Ying, the roots and rhizomes of Dysosma furfuracea S.Y. Bao and the podophyllotoxin, deoxypodophyllotoxin of Guijiu plants in mice. Methods Tumor borne mice with transplanted HepA and Ehrlich ascites carcinoma (EAC) were used to observe the antitumor and the liver protective effects of the above five samples, which were given orally. Results Extracts of roots and rhizomes of S. emodi, and D. furfuracea showed the significant antitumor effects. Conclusion All the five samples have antitumor activity.
