Serum Anti-Saccharomyces Cerevisiae Antibodies in Greek Patients with Behcet's Disease.
10.3349/ymj.2011.52.2.347
- Author:
George VAIOPOULOS
1
;
Peter Laszlo LAKATOS
;
Maria PAPP
;
Faedon KAKLAMANIS
;
Efrosyni ECONOMOU
;
Vassilis ZEVGOLIS
;
John SOURDIS
;
Kostas KONSTANTOPOULOS
Author Information
1. First Department of Medicine, Athens University Medical School, Athens, Greece. kkonstan@med.uoa.gr
- Publication Type:Brief Communication ; Research Support, Non-U.S. Gov't
- Keywords:
Anti-Saccharomyces cerevisiae antibodies;
Behcet's disease;
Greece
- MeSH:
Adolescent;
Adult;
Aged;
Antibodies, Fungal/*immunology;
Behcet Syndrome/*immunology/microbiology;
Case-Control Studies;
Female;
Greece;
Humans;
Immunoglobulin A/immunology;
Immunoglobulin G/immunology;
Male;
Middle Aged;
Saccharomyces cerevisiae/*immunology;
Young Adult
- From:Yonsei Medical Journal
2011;52(2):347-350
- CountryRepublic of Korea
- Language:English
-
Abstract:
We tested 59 Greek patients with Behcet's Disease (BD) for serum anti-Saccharomyces cerevisiae antibodies. No increase of these antibodies was detected in the cases compared to 55 healthy unrelated blood donors from the same population. This finding is in contrast with the correlation between Saccharomyces cerevisiae antibodies and BD as reported in other populations. It seems that environmental factors may contribute to disease expression in different populations, producing different effects according to the individual's genetic predisposition. Saccharomyces cerevisiae antibodies do not seem to be of any significance in the Greek population.