Study on the transdermal releasing rule of the preparation of Jiufen Spray
- VernacularTitle:九分喷雾剂透皮释放率研究
- Author:
Yiqun SUN
;
Liling ZHOU
;
Xiaoyin CHEN
;
- Publication Type:Journal Article
- Keywords:
Jiufen powder;
spray;
transdermal study;
releasing ratio
- From:
Chinese Traditional Patent Medicine
1992;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the transdermal releasing rule of the preparation of Jiufen Spray.Methods: Improved Franz diffuser was applied to transdermal experiment with TLC scanning method.Results: Q T (quantum time) equations of Jiufen Spray are strychnine:Q=220.941t- 486.006 , brucine:Q=208.146t-454.629, ephedrine:Q=177.691t-247.826. The study on releasing rule suggests the accumulative amount of transdermal drug increases with time, but the releasing speed is roughly stable, the total releasing ratio of 12 hours is about 50%. Conclusion: Jiufen spray could surmise to maintain relatively stable plasma drug concentration.
