Study on physicochemical properties of storax ?-cyclodextrin inclusion complex
- VernacularTitle:苏合香?-环糊精包合物的理化性质考察
- Author:
Hongtao SONG
;
Tao GUO
;
Minghong ZHAO
;
Ruhua ZHANG
;
Xian LI
;
- Publication Type:Journal Article
- Keywords:
storax;
? cyclodextrin (? CD);
inclusion complex;
physiochemical properties
- From:
Chinese Traditional and Herbal Drugs
1994;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Object To study the phsiochemical properties of storax ? cyclodextrin (? CD) inclusion complex Methods The inclusion complex was identified by the methods of TLC, X ray powder diffractometry and IR The solubility and dissolution rate of cinnamic acid in inclusion complex were investigated by HPLC Results The TLC showed that the main composition of storax had no change before and after being included by ? CD The spectra of X ray powder diffractometry and IR of the inclusion complex were remarkably different from those of storax and storax ? CD mixture It was shown a great improvement of the solubility and dissolution rate of cinnamic acid in the inclusion complex in 0 1 mol/L HCl, pH 6 6 and pH 7 5 phosphate buffer solution Conclusion The storax ? CD inclusion complex exhibits some new physical characteristics and its physiochemical properties are greatly changed comparing with those of storax
