Effect of ultrafiltration conditions on content of aconitines, glycyrrhizic acid and solid residue in Sini Decoction
- VernacularTitle:不同超滤条件对四逆汤中乌头总碱、甘草酸及固含量的影响
- Author:
Luosheng HUANG
;
Jianxin GUO
;
- Publication Type:Journal Article
- Keywords:
Sini Decoction;
ultrafiltration;
aconitines glycyrrhizic acid
- From:
Chinese Traditional Patent Medicine
1992;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the effect of ultrafiltration conditions on the content of aconitines, glycyrrhizic acid and solid residue in Sini Decoction water (A), 40% ethanol (B) and 60% ethanol (C) solution. Methods: Ion pair extraction combined with UV spectrophotometry, TLC combined with UV spectrophotometry and weighing method have been used respectively to detect the content of aconitines, glycyrrhizic acid and weight of dry extractum. Results: Results showed the losses of aconitines and glycyrrhizic acid were inversely proportional to the size of ultrafiltration membrane and the concentration of ethanol. The loss of glycyrrhizic acid was larger than 10%. The decrease of solid residue was proportional to the loss of glycyrrhizic acid. Conclusion: Ultrafiltration of Sini Decoction in water, 40%～60% ethanol solution cannot eliminate impurities.
