Determination of glycyrrhizic acid in Gankang Granules by HPLC
- VernacularTitle:HPLC测定肝康颗粒中甘草酸的含量
- Author:
Lidan HUANG
;
Jiayi KAN
;
Bin JIN
;
- Publication Type:Journal Article
- Keywords:
Gankang Granules;
glycyrrhizic acid;
HPLC
- From:
Chinese Traditional Patent Medicine
1992;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To determine glycyrrhizic acid content in Gankang Granules by HPLC.Methods: HPLC analysis was carried out with C 18 column and methanol acetic acid water (65∶5∶30) as the mobile phase. The detection wavelength was 250nm.Results: The linear range was 9.78~58.68 ?g( r=0.9999 n=6) . The average recovery was 98.40%, RSD was 0.88%. Conclusion: The method is simple, reliable and sensitive. It can be used in quality control of Gankang Granules.