Serum-pharmacological effects of Stellera chamaejasme L. abstract with water on proliferation of gastric adnocacinoma SGC-7901 Cells
- VernacularTitle:瑞香狼毒水提物小鼠药物血清对人胃腺癌SGC-7901细胞增殖的影响
- Author:
Xiaolan JIAO
;
Zhengping JIA
;
- Publication Type:Journal Article
- Keywords:
stellera chamaejasme L.;
serum pharmacology;
gastric adnocacinoma SGC 7901 cultural cells
- From:
Chinese Traditional Patent Medicine
1992;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the anticancer mechanism of Stellera chamaejasme L. abstracts with water (SCLA). Methods: SCLA drugserum was derived after different time from mice which was orally peradministrated with different dose of SCLA. the effects of the serum on the roliferation of human gastric adnocacinoma SCG7901 cells were observed with MTT assay and clone formation methods.Results: After treatment with the drugserum derived at 1,2,3h from mice pertreated with SCLA(5,10 and 20g?kg -1 ), the MTT formazan and cone formation of gastric adnocacinoma SGC7901 cells were decreased significantly. SCLA from the mice which were given the drugserum 2h later was more effective than others. Conclusions: SCLA had a remarkable inhibitory effects on proliferation of gastric adnocacinoma SGC7901 cells, which may be the main anticancer mechanisms of SCLA.
