Investigation of influential factors on TONGMAI HUANSHUAN CAPSULE packing variation
- VernacularTitle:通脉化栓胶囊装量差异的影响因素考察
- Author:
Wangwen GU
;
Peiqiong XIA
;
Xianwu JIANG
;
- Publication Type:Journal Article
- Keywords:
Tongmaihuanshuan;
capsule;
packing variation
- From:
Chinese Traditional Patent Medicine
1992;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate several factors influencing Tongmaihuashuan Capsule packing variation. Methods:To prepare Tongmaihuashuan granule with different granule size and distribution. To add the talcum for 0,2%,5% in order to increase its fluidity and to place the granule under the different humidity in order to maintain different water content. To fill the capsule with these granules by the capsule filling machine with the rotating velocity of 1100r/min and 1430r/min, respectively. To determine precisely the capsules average weight and compare their weight standard deviation. Results: When the granule size of “b” is more uniform than that of “a”, the weight standard deviation of “b” and “a” are 0.0525g and 0.0623g, respectively. When the talcum is added for 0,2%,5%, the weight standard deviation are 0.064g, 0.052 g and 0.047g, respectively. When the water content of granule are 2.4%, 4.1%, 9.8%, the weight standard deviation are 0.043g, 0.064g, 0.075g . When the velocity of capsule filling machine are 1100r/min and 1430r/min, the weight standard deviation are 0.053g and 0.062g. Conclusion: The granule size, fluidity, water content and the velocity of capsule filling machine influence Tongmaihuashuan capsule packing variation. In order to control the capsule quality, these factors should be considered and optimized.