Comparison study on effects of decoction and extract of Rehmannia Glutinosaon peripheral hemogram in mice
- VernacularTitle:熟地水煎剂及其提取物对小鼠外周血象影响的比较研究
- Author:
Xia HUANG
;
Hui QING
;
Huisen WANG
;
Huixia LIU
;
- Publication Type:Journal Article
- Keywords:
Rehmannia glutinosa;
decoction extract;
peripheral hemogram
- From:
Chinese Traditional Patent Medicine
1992;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the effects of Rehannia glutinosa decoction (RGD)、 Rehmannia glutinosa polysaccharide (RGP) and Rehmannia glutinosa non polysaccharide (RGNP) on peripheral hemogram in mice. Methods: The first experimental group were continuously given RGD、RGP and RGNP for nine days, and then blood sample was taken from tails for determination of peripheral hemogram. The second group were given RGD、RGP and RGNP for five days, after making the blood difficiency model of cyclophosphamide. Determinating peripheral hemogram of the third group, after that those mice were given cyclophosphamide by 2 days, 4 days, 6 days, 8 days. Results: Peripheral hemogram of the every normal group has no difference. To compare the model of blood difficiency group and the control group, there were significant differences, RGNP can only enhance WBC. Both RGP and RGNP can reduce WBC of the mice model of anti cyclophosphamide, while RGP was superior to RGNP. Conclusion: Rehmannia glutinosa has dual directional adjustment function. RGP is tonifying blood active fraction of RG.